Bactericidal and bacteriostatic; inhibits protein synthesis after binding with 50S ribosomal subunit of susceptible organisms. Demonstrates cross-resistance to erythromycin-resistant gram-positive strains and resistance to most strains of Enterococcus faecalis and methicillin-resistant Staphylococcus aureus. pneumoniae Adults: Instill 1 drop in affected eye(s) b.i.d., 8 to 12 hours apart for first 2 days; then instill 1 drop in affected eye(s) once daily for next 5 days Mild community-acquired pneumonia Adults: 500 mg P. Oral suspension: 100 mg/5 ml in 15-ml bottles; 200 mg/5 ml in 15-ml, 22.5-ml, and 30-ml bottles Oral suspension (Zmax extended-release): 2-g bottle Powder for injection: 500 mg in 10-ml vials Powder for oral suspension: 100 mg/5 ml, 200 mg/5 ml, 1,000 mg/packet Solution (ophthalmic): 1% in 5-ml bottle filled with 2.5 ml solution Tablets: 250 mg, 500 mg, 600 mg Tablets (Tri-Pak): three 500-mg tablets Tablets (Z-Pak): six 250-mg tablets Bacterial conjunctivitis caused by CDC coryneform group G, H. aureus Adults and adolescents ages 16 and older: 500 mg I. (no more than 500 mg/dose) on day 1, then 5 mg/kg (no more than 250 mg/dose) for 4 more days Community-acquired pneumonia caused by Chlamydia pneumoniae, Haemophilus influenzae, Mycoplasma pneumoniae, Streptococcus pneumoniae, Legionella pneumophila, Moraxella catarrhalis, and S. Infectious disease A broad-spectrum once-daily advanced-generation macrolide antibiotic used to manage community-acquired and other pneumonias caused by S pneumoniae, H influenzae, Moraxella catarrhalis, C pneumoniae, M pneumoniae, chlamydial infections, UTIs, MAC, possibly also toxoplasmosis and cryptosporidiosis Adverse effects Diarrhea, N&V, abdominal pain, vertigo, photosensitivity, hearing loss, injection site pain Relative contraindications Cystic fibrosis, nosocomial infections, bacteremia, elderly, debilitated Pts. n brand name: Zithromax; drug class: macrolide antibiotic; action: binds to 50S ribosomal subunits of susceptible bacteria and suppresses protein synthesis; similar spectrum of activity to erythromycin; uses: infections of the upper and lower respiratory tract, uncomplicated skin infections. daily for a total of 7 to 10 days Children ages 6 months to 16 years: 10 mg/kg P. 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(2R,3S,4R,5R,8R,10R,11R,12S,13S,14S)-11-((2S,3R,4S,6R)- 4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-2-ethyl-3,4,10-trihydroxy-13-((2S,4R,5S)-5-hydroxy-4-methoxy-4-methyltetrahydro-2H-pyran-2-yloxy)-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-on Azithromycin ist eine organische chemische Verbindung aus der Gruppe der Glycoside, der als antibiotisch wirkender Arzneistoff der Gruppe der Makrolid-Antibiotika eingesetzt wird. Mittlerweile klassifiziert man den Wirkstoff auch als ersten Vertreter der Azalide. Eine Forschergruppe des pharmazeutischen Unternehmens Pliva in Zagreb im damaligen Jugoslawien um Slobodan Dokić, Gabrijela Kobrehel, Gorjana Radobolja-Lazarevski und Zrinka Tamburašev entdeckte Azithromycin 1979/1980. Es wurde 1981 patentiert und war ab 1988 als Sumamed im Bereich des sozialistischen Mittel-Osteuropas erhältlich. Bereits 1986 wurde mit Pfizer ein Vertrag geschlossen, der diesem 1991 die Markteinführung in Westeuropa und außerhalb Europas unter dem Handelsnamen Zithromax ermöglichte. Azithromycin findet Anwendung bei Infektionen der Atemwege einschließlich Lungenentzündungen, akuter Exazerbation der chronischen Bronchitis, Nasennebenhöhlenentzündungen, Entzündungen im Rachenbereich und Mandelentzündungen. Weiterhin wird Azithromycin bei akuten Mittelohrentzündungen, Haut- und Wundinfektionen, Lyme-Borreliose, bakterieller Konjunktivitis, bei Urethritis durch Chlamydien und zur Prophylaxe sogenannter MAK-Infektion (Mycobacterium-avium-intrazellulare-Komplex-Infektion) bei immungeschwächten Patienten verwendet. Zithromax tri pak Zithromax Tri Pak Best Prices Excellent Quality, Zithromax TRI-PAK vs Zpak - Treato Cialis online cheap from canada Legal buy viagra online ireland Viagra band Zithromax Tri Pak Directions LocalPharmacy Prices for Generic Viagra Online! 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Azithromycin az-ith″ro-mi´sin a macrolide antibiotic derived from erythromycin, effective against a wide range of gram-positive, gram-negative, and anaerobic bacteria.