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    5 mg prednisolone (as acetate), USP For steroid therapy, as an aid in the treatment of arthritis, asthma, skin disorders, allergic dermatoses and other inflammatory conditions in dogs and cats. Prednisolone 5 mg tablets are for oral administration. The dosage, as with other corticosteroids, should be individualized according to the severity of the conditions, anticipated duration of therapy and the patient's threshold or tolerance for steroid excess. For chronic conditions, the lowest dose producing adequate relief should be the one employed. As a guideline, Dogs: 0.5-1.0 mg/kg Cats: 1-2 mg/kg Doses should be given as single or divided doses initially and then tapered to every 48 hours. Prednisolone 5 mg tablets contain a potent steroid and are to be used under the direct supervision of a veterinarian. All precautions and contraindications for adrenocortical hormones must be observed. Prednisolone is a synthetic corticosteroid with approximately four times the anti-inflammatory potency of hydrocortisone. Corticosteroids have an effect on practically every system of the body. They are important in normal protein, carbohydrate and fat metabolism, and for their role in controlling inflammation. They have both strong beneficial effects and a definite potential to cause negative side-effects. Prednisolone commonly is used in both small- and large-animal veterinary medicine. It may be given by injection, orally, ophthalmically, or topically. Preparations for topical use may include other active ingredients such as antibiotics, antifungals, or miticides.

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