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Use as needed for ED: -Initial dose: 10 mg orally once a day, as needed, prior to sexual activity -Maintenance dose: 5 to 20 mg orally once a day, as needed, prior to sexual activity based on individual efficacy and tolerability Comment: Consider that this drug has shown to improve erectile dysfunction up to 36 hours following dosing, when used as needed. Once a day use for ED: -Initial dose: 2.5 mg orally once a day at approximately the same time, without regard to timing of sexual activity -Maintenance dose: 2.5 to 5 mg orally once a day based on individual efficacy and tolerability. Once daily use for ED and Benign Prostatic Hyperplasia (BPH): -5 mg orally once a day at approximately the same time, without regard to timing of sexual activity Use: Treatment of erectile dysfunction (ED) Adcirca (R): -40 mg orally once a day Comment: Dividing the 40 mg dose over the course of the day is not recommended. 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