Plaquenil (hydroxychloroquine) belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Plaquenil side effect skin Plaquenil medication side effects I was told I didn't have to taper it like prednisone, and that I shouldn't expect any rebound type of reaction like you get when your body adjusts to being off pred. But everyone is taking a different mix of drugs and maybe you're taking something I don't that would make your doctor's recommendation for you different. It happens with both doses. The other one has to do with "ringing" in the ears. I had started with some tinnitus before the medication but have noticed it is worse in the last 3 or 4 weeks. "Can you stop Plaquenil cold turkey" answer - YES. My rheumy told me to take time out on it for a month once. I was put on Plaquenil for RA as I was being dx for lupus. I am very mild. My rhuemy wants me to stop every time I have an infection. When it is gone she said I can resume at my own pace. Take into consideration I only take Plaquenil and ibuprofen 800mg. My symptoms came back after two weeks of being off it. This medicine is not effective against all strains of malaria. Malaria is common in areas such as Africa, South America, and Southern Asia. What can happen if you stop taking plaquenil What happens if I stop taking plaquenil., Can you quit plaquenil cold turkey, or have to wean Plaquenil eye exam costChloroquine phosphate costPlaquenil side effects antimalarial Take Plaquenil EXACTLY as prescribed by your physician. Do not stop taking the medication without first speaking to your doctor. Taking Hydroxychloroquine with food and/or milk can help prevent stomach upset. If you miss a dose, take it as soon as you remember. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Stopping Plaquenil - General Discussion - Life With Lupus. Can you just stop taking plaquenil or do you have to wean.. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up. Aug 28, 2012 Plaquenil hydroxychloroquine takes a long time to get out of the system - up to 18 months. Be certain you and your physician agree you should discontinue it. HealthTap does not provide medical advice, diagnosis, or treatment. For these services, please use HealthTap Prime or Concierge. See Additional Information. If you are taking Plaquenil to treat an inflammatory condition or malaria, you should be aware of the side effects that may occur to your eyes and vision. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage.