Tamoxifen and hydroxychloroquine

Discussion in 'Reliable Pharmacy' started by angelinam, 28-Feb-2020.

  1. int21hi New Member

    Tamoxifen and hydroxychloroquine


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    WebMD provides information about interactions between Hydroxychloroquine Oral and weak-cyp2d6-inhibitors-tamoxifen. Hydroxychloroquine. In the United States, Plaquenil hydroxychloroquine, Sanofi-Aventis is commonly used to treat rheumatic conditions such as rheumatoid arthritis, systemic lupus erythematosus and Sjögren’s syndrome. Tamoxifen competes with estradiol for receptors in breast. Hydroxychloroquine is a well-tolerated medication for various rheumatologic and dermatologic conditions. Its main side effects are gastrointestinal upset, skin rash, headache, and ocular toxicity1. Within the eye, hydroxychloroquine can adversely impact the cornea, ciliary body, and retina1

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    Tamoxifen and hydroxychloroquine

    The risk of toxic retinopathy in patients on long-term., Know Your Systemic Meds The Top 10 to Track

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  6. This article is from June 2011 and may contain outdated material. Download PDF. Many systemic medications may cause retinal toxicity. One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine Plaquenil, a chloroquine derivative.

    • Hydroxychloroquine-Induced Retinal Toxicity - American Academy of..
    • Hydroxychloroquine toxicity - EyeWiki.
    • Drug induced maculopathy - EyeWiki.

    Tamoxifen is a widely used breast cancer drug but some women with advanced, postmenopausal estrogen receptor-positive ER+ breast cancer don't respond to it. A study in Clinical Cancer Research found that the inexpensive anti-malarial drug hydroxychloroquine HCQ reverses resistance to tamoxifen in mice, meaning that adding HCQ to tam Safety and efficacy of hydroxychloroquine to treat lupus and arthritis have not been established in children. Geriatric. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of hydroxychloroquine in the elderly. We found that inhibiting autophagy through low-dose oral hydroxychloroquine HCQ administration increases the responsiveness of resistant mammary tumors to antiestrogens. Moreover, we show that the combination of tamoxifen and HCQ is more effective than that of Faslodex and HCQ due to activities within the tumor microenvironment.

     
  7. y11! New Member

    Chloroquine is the generic form of the brand-name prescription medicine Aralen, which is used to prevent and treat malaria — a mosquito-borne disease caused by a parasite — and to treat amebiasis, an infection of the intestines caused by a parasite. Chloroquine Aralen - Side Effects, Dosage, Interactions. Coronavirus Chloroquine can have deadly side effects Chloroquine - Wikipedia
     
  8. Evgenij Moderator

    Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Hydroxychloroquine Uses, Dosage & Side Effects - Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses
     
  9. LexxAgon Moderator

    ACR Actual-weight hydroxychloroquine dosing works in SLE. SAN FRANCISCO – Hydroxychloroquine Plaquenil dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus SLE, according to a review of 686 lupus patients at Johns Hopkins University in Baltimore. Most were dosed by actual weight, 6.5 mg/kg up to a maximum of 400 mg/day.

    PLAQUENIL® - Food and Drug Administration