Tamoxifene

Discussion in 'Prescription Drugs Online Without' started by Ludmila672, 06-Sep-2019.

  1. arkmor Well-Known Member

    Tamoxifene


    – пауза) – этап в жизни женщины между прокреационным возрастом и началом старения. Месячные при климаксе могут вести себя как разбалансированный механизм. Бояться этого не следует, как любого нормального физиологического процесса. Этот период жизни связан с затуханием деятельности гонад – органов, вырабатывающих половые клетки – гаметы. Яичники выделяют яйцеклетки, прогестины и эстрогены. Но организму уже не нужно нести «прокреационную службу», поэтому он естественным образом изменяется. В процессе этой перестройки – от 40-45 лет и до полного наступления климакса — возможны всяческие колебания цикла, и женщина беспокоится: почему месячные перестали? Или наоборот: почему после сорока у меня месячные два раза в месяц? Потому что мы вступаем в интересный возраст изменения, который длится 1-2 года. Tamoxifen ist ein selektiver Estrogenrezeptormodulator, der als Arzneistoff zur Therapie von Brustkrebs bei Frauen vor der Menopause eingesetzt wird. Tamoxifen wurde von ICI Pharmaceuticals (jetzt Astra Zeneca) entwickelt und bewirkt eine kompetitive Hemmung von Estrogenrezeptoren sowie eine Stimulation von Progesteronrezeptoren. Als „Vater“ der Brustkrebs-Behandlung mit Tamoxifen gilt V. Auch zur Therapie von fibrozystischen Brüsten wurde bei Frauen Tamoxifen angewendet, um Knoten, Schwellungen und Schmerzen zu reduzieren. Forscher der Universität San Diego sollen 2018 herausgefunden haben, dass Tamoxifen gegen die Amöbe Naegleria fowleri wirken soll. Diese löst bei Menschen die in bis zu 95 % der Fälle tödlich verlaufende Primäre Amöben-Meningoencephalitis aus. Als Hormonrezeptormodulator kann Tamoxifen potenziell die Wirkung anderer Hormonpräparate beeinflussen. Insbesondere bei gleichzeitiger Einnahme von Estrogenen mit Tamoxifen kann eine wechselseitige Wirkungsabschwächung beobachtet werden.

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    Хорошо всасывается из ЖКТ, Tmax — 4–7 ч, время достижения Css — 3–4 нед. Связывание с белками плазмы — 99%. Метаболизируется в печени путем гидроксилирования и. Tamoxifen, sold under the brand name Nolvadex among others, is a medication that is used to prevent breast cancer in women and treat breast cancer in women and men. One of the SELECTIVE ESTROGEN RECEPTOR MODULATORS with tissue- specific activities. Tamoxifen acts as an anti-estrogen inhibiting agent in the.

    Tamoxifen won't work on hormone-receptor-negative breast cancer. Tamoxifen is available in two forms: a pill taken once a day (brand name: Nolvadex) or a liquid form (brand name: Soltamox). If you dislike pills or you're having trouble swallowing tamoxifen pills, Soltamox can help make it easier to stay on your treatment plan. Most doctors recommend taking tamoxifen at the same time each day. — while you are taking tamoxifen and for 2 months afterward. You should not take tamoxifen if you are breastfeeding, pregnant, trying to get pregnant, or if there is any chance that you could be pregnant. You should use an effective non-hormonal type of birth control — such as condoms, a diaphragm along with spermicide, or a non-hormonal I. Ask your doctor which type of non-hormonal birth control would be best for you. Since its approval in 1998, tamoxifen has been used to treat millions of women and men diagnosed with hormone-receptor-positive breast cancer. While an aromatase inhibitor is the first hormonal therapy medicine choice for postmenopausal women, tamoxifen is the first choice for premenopausal women and is still a good choice for postmenopausal women who can't take an aromatase inhibitor. In the US, Tamoxifen (tamoxifen systemic) is a member of the following drug classes: hormones/antineoplastics, selective estrogen receptor modulators and is used to treat Breast Cancer, Breast Cancer - Adjuvant, Breast Cancer - Male, Breast Cancer - Metastatic, Breast Cancer - Palliative, Breast Cancer - Prevention, Mc Cune-Albright Syndrome and Precocious Puberty. US matches: Further information on drug naming conventions: International Nonproprietary Names. Important Notice: The international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.

    Tamoxifene

    DB00675 Tamoxifen - Tamoxifen - DrugBank, Tamoxifen - Wikipedia

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  5. Le tamoxifène a été employé pendant plusieurs années pour traiter le cancer du sein qui est hormone récepteur-positive. C'est à cause de sa capacité de bloquer compétitif l'oestrogène grippant aux.

    • Effets secondaires de tamoxifène.
    • Tamoxifen C26H29NO - PubChem.
    • Soltamox tamoxifen dosing, indications, interactions, adverse..

    Informazioni sul farmaco antitumorale Tamoxifene che cos'è, come si somministra, quali sono i potenziali effetti collaterali. Tamoxifene EG citrate tablets are indicated for the treatment of node-positive breast cancer in women following total mastectomy or segmental mastectomy, axillary dissection, and breast irradiation. Tamoxifen may cause cancer of the uterus womb, strokes, and blood clots in the lungs. These conditions may be serious or fatal. Tell your.

     
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  7. Martin Well-Known Member

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