Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine lc3b Is plaquenil used for osteoarthritis What Exactly Is Hydroxychloroquine, The Drug That Is Being Tested As The First Potential Coronavirus Treatment. responsible for inflammation and other general disease symptoms e.g. pain, fever. If the maximum daily dosage recommendations are followed, the likelihood of toxicity from chloroquine or hydroxychloroquine is less than 1% the first five years of treatment. Corneal epithelial changes are usually reversible, but retinopathy caused by these agents are not. If you are taking hydroxychloroquine for symptoms of rheumatoid arthritis, your symptoms should improve within 6 months. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Once you and your doctor are sure the drug works for you. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Symptoms of hydroxychloroquine toxicity Plaquenil Side Effects Common, Severe, Long Term -, Chloroquine and Hydroxychloroquine Toxicity Practice. Plaquenil causing low blood sugarPlaquenil dermatomyositis After seeing MANY professionals including a neurologist, a retinal specialist, neuro-ophthalmologist, and undergoing MANY different tests, she was diagnosed with Plaquenil toxicity. She does have field of vision loss, mostly on things that are close up. She took Plaquenil for almost five years before having any symptoms. Has anyone experienced plaquenil toxicity with damage to eyes?. Hydroxychloroquine MedlinePlus Drug Information. Chloroquine and Hydroxychloroquine Toxicity Clinical.. Symptoms and Signs. Symptoms. Patients in earlier stages of hydroxychloroquine retinal toxicity usually do not experience symptoms, though the rare patient may note a paracentral scotoma that causes trouble with reading as well as diminished color vision. However, most patients usually notice symptoms only after scotomas have become severe. Individuals beginning HCQ therapy should be informed of the possibility, although extremely rare, of retinal toxicity, and told that periodic monitoring can lead to early recognition of some symptoms. Hydroxychloroquine is the most commonly used AM, specifically because it has a lower risk for retinal toxicity than chloroquine. Call a poison control center at once and then seek emergency medical attention if you think you have used too much of this medicine. An overdose of hydroxychloroquine can be fatal, especially in children. Take hydroxychloroquine for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared.