Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. How does chloroquine phosphate work Www plaquenil Plaquenil reviews side effects Plaquenil toxicity in macular oct A 57-year-old female presented to the Ophthalmology clinic at UIHC complaining bilateral central photopsias for the past two years. She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine Plaquenil 200mg bid 6.5mg/kg for 10 years, which was stopped one year prior to. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight. One kilogram kg equals 2.2 pounds. Women with lupus who are OVER their ideal body weight should go by these dosing rules 5’ 7” or higher - up to 400 mg Plaquenil daily Hydroxychloroquine Plaquenil is a chloroquine derivative used in the treatment of many diseases including malaria, rheumatoid arthritis, and systemic lupus erythematosus. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Fundus autofluorescence plaquenil Early Plaquenil Toxicity Detected without Bull’s Eye Maculopathy, Protecting your eyesight when taking Plaquenil Lupus. Easy bruising plaquenilTaking plaquenil high dosePlaquenil adverse reactionsHydroxychloroquine quinineHydroxychloroquine plaquenil for malaria in peru Fundus autofluorescence FAF is a non-invasive imaging technique that detects fluorophores, naturally occurring molecules that absorb and emit light of specified wavelengths 1. To produce autofluorescence, a fluorophore absorbs a photon of the excitation wavelength, which elevates an electron to an excited, high energy state. Clinical applications of fundus autofluorescence in.. Unusual Fundus Autofluorescence Appearance in a Patient.. Multimodal Imaging in Plaquenil Toxicity. Although multifocal electroretinogram mfERG and fundus autofluorescence FAF are not currently primary tests used in the evaluation of Plaquenil retinal toxicity, they may be beneficial when the diagnosis or findings are enigmatic or an adjunct test is warranted. Jan 01, 2011 Fundus autofluorescence is a noninvasive, rapid and potentially useful imaging modality that continues to evolve. FAF reflects metabolic changes in the RPE and thus provides an assay of retinal and RPE function. Fundus autofluorescence FAF is a non-invasive, high definition scan of the deeper retinal layers at the back of the eye. FAF highlights areas of metabolic stress in detail that is above and beyond that of conventional retinal cameras.