It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Hydroxychloroquine high anion gap ketoacidosis Dapsone hydroxychloroquine Plaquenil hydroxychloroquine is associated with a variety of rashes, and you should discuss with your doctor if a medication change would be the best treatment for your rash. Read more. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Sep 13, 2019 Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Plaquenil for skin rash Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Hydroxychloroquine MedlinePlus Drug Information Plaquenil painful muscle spasmsHydroxychloroquine sickle cell dosePlaquenil hydroxychloraquineBuy plaquenil ukCan i tan on plaquenil Plaquenil is available in generic form. What Are Side Effects of Plaquenil? Common side effects of Plaquenil include. nausea, vomiting, stomach pain or cramps, loss of appetite, weight loss, diarrhea, dizziness, spinning sensation, headache, ringing in your ears, mood changes, nervousness, irritability, skin rash, itching, or; hair loss. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Plaquenil Side Effects Common, Severe, Long Term -. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Skin rashes and pigment change. Atabrine, specifically, can cause yellow pigmentation of skin. Sometimes Plaquenil can also deposit in the tissues of the body and cause the skin to take on a greenish tone. Quinacrine Atabrine Quinacrine is another alternative, but it is prescribed less often because it can sometimes cause a yellow discoloration of the skin. It is sometimes given in addition to hydroxychloroquine if the Plaquenil on its own is not adequately managing symptoms. Only a compounding pharmacist can dispense Quinacrine as tablets are. Rash from plaquenil. deleted_user 10/30/2011. I have been on plaquenil for about 3 weeks and I am starting to get a itchy rash. It's pretty mild so far starting on my forearms and now on my chest a little and the rest of my arms. Has anyone else had this problem? Will it go away? I am going to call my doc tomorrow but just wanted someone's opinion.