At first it seemed like it helped now I feel the same as before I started taking the medicine other than the fact that none of my clothes fit and there is a lot more of me to carry around. Anyone know if I quit taking it if the weight will fall back off I started Hydroxychloroquine 2 weeks ago. One week in and I thought this may just work, except for the ‘extra itchiness’ I seemed to get every night. Does plaquenil weaken the immune system Can plaquenil cause ankle swelling Plaquenil retinopathy oct images Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America. Hello all, I am currently new to this site and ran across the discussion about stopping Plaquenil. I have been taking Plaquenil for about 8-9 months and thought that it was not helping me because I still have a fair amount of joint pain, fatigue, muscle pain and so many other issues. I was prescribed this drug to ease my ra disease, I was taking 400mg per day which was to last for 3 months then reduced to 200mg. Right before I hit the two week mark, I woke up with my heart racing and continued feeling my heart flutter all day and I just felt week and tired. After msging Rheum, decided to stop taking meds to see how I feel and continue with the AIP to handle symptoms and try to work at ‘healing from inside out! Time will tell and I’m eager to see how much the AIP is helping once odd meds. Hydroxychloroquine discontinue Had to stop taking Plaquenil -, Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs. Is hydroxychloroquine a narcotic Side Effects. Drug information provided by IBM Micromedex Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Stopping plaquenil. DailyStrength. Hydroxychloroquine Oral Route Proper Use - Mayo Clinic. Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. The retinopathy does not reverse, but the progression is rare after hydroxychloroquine is discontinued. Visual symptoms may present as paracentral scotomas islands of vision loss when reading. If blurring or vision changes occur, hydroxychloroquine should be ceased, and a careful eye examination conducted. Hydroxychloroquine received an overall rating of 7 out of 10 stars from 368 reviews. See what others have said about Hydroxychloroquine, including the effectiveness, ease of use and side effects.