I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Chloroquine resistant salmonella Herpes and plaquenil Hydroxychloroquine and chloroquin sarcoidosis Opthalmologist baseline test for plaquenil bethlehem Those who stopped it abruptly had real problems similar to what you are experiencing. If you really need to get off it, I would taper down slowly, very slowly. There is a similar posting on Healthunlocked, "Why oh why did u stop taking plaquenil." You may want to check it out. Hi, for anyone that's been on plaquenil long term i've been on more than 2 1/2 years, have you had any moderate to bad flares or flares that dont' seem to go away while taking this med? Or has anyone found that plaquenil stopped working after some time? I've been in some sort of flare for 6 weeks So that's the update. The lesson here is - for those who need to go off plaquenil, be careful about just going off it cold turkey. Obviously some of CAN do that, but if you don't know if you're one of them - better to be on the safe side and wean slowly. Take it from me! I am feeling much better after bumping my dose back up over the last few. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Ddo you have to stop plaquenil slowly Plaquenil Hydroxychloroquine - Side Effects, Dosage., Immune & Autoimmune - Lupus Flares While Taking Plaquenil Can plaquenil cause glaucomaPlaquenil and coumadin interactionChloroquine injection side effects Plaquenil is supposed to stay in your system for 1-2 months after you stop taking it. Try to rest, stay hydrated and away from sick ppl for now and hopefully you will not have any issues Stopping Plaquenil - General Discussion - Life With Lupus. Let me tell you what weaning down from Plaquenil is like.. Conditions Plaquenil-related Eye Problems Eugene Eye Care. Question Four years ago, I was diagnosed with osteoarthritis OA in my right ankle. Now X-rays show OA in my spine, neck, knuckles, wrists and knees. Can you tell me what caused OA to spread this way, and is there anything I can do to stop it? How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. In children, dosage is also based on weight. Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. If you're gonna experiment, I went off it cold turkey as it didn't hurt to do it that way, but you better get back on before the summer or you could experience a flare-up.