Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Cost for hydroxychloroquine Does plaquenil help raynaud's Plaquenil tremors Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs. If you have had any eye changes or changes in eyesight due to hydroxychloroquine or drugs like this one. If you have psoriasis. A side effect of some RA medicine is sun sensitivity. Be extra careful to avoid skin burns, blistering, and the infections that may result. Because her history was negative for sun-sensitivity and her blood did not contain SS-A antibodies, I elected to discontinue Plaquenil and treat the skin with narrow-band ultraviolet B light. The patient tolerated the ultraviolet light without any complications, and the psoriasis improved. Comment. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Plaquenil and sun sensitivity Sun allergy - Diagnosis and treatment - Mayo Clinic, Rheumatoid Arthritis Medication Beware of Sunburn if You. Baseline testing for plaquenilMethotrexate and plaquenil treatmentHydroxychloroquine combination Find patient medical information for Plaquenil Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Plaquenil Oral Uses, Side Effects, Interactions, Pictures.. Psoriasis Associated with Plaquenil Hydroxychloroquine - Dr.. Lupus and Sun Exposure. Photoallergic reactions are caused by the reaction of a topical ointment with UV radiation. Topical ointments are applied directly to the skin. Reactions may develop after one to 10 days of exposure but often recur within 24 to 48 hours of re-exposure. Started small, but ended being an extreme sun triggered allergy to plaquenil that covered most of my body. It's been 4 months and it's still tapering off. It was/is extreme, and almost certainly a different reaction than what you got, but would like to echo others saying to be very careful of the sun. My rheum didn't warn me about sun sensitivity. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.