Treatment of discoid lupus erythematosus with chloroquine

Discussion in 'Chloroquine Drug' started by HepB, 09-Mar-2020.

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    Treatment of discoid lupus erythematosus with chloroquine


    Although survival rates have improved, over one half of patients with systemic lupus erythematosus have permanent damage in one or more organ systems. Arthritis and cutaneous manifestations are most common, but renal, hematologic and neurologic manifestations contribute largely to morbidity and mortality.

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    Treatment of discoid lupus erythematosus Begin treatment with the elimination of foci of chronic infection in the body, the normalization of endocrine disorders. Eliminate other irritating and provoking factors, such as direct sunlight, radiation therapy, cold, drafts, external skin damage. Successful Treatment of Discoid Lupus Erythematosus with Chloroquine Laurentius A. Pramono, Resultanti, Suryo Anggoro, Sandra Langow, Rudy Hidayat, Bambang Setyohadi, Harry Isbagio Original Article from The New England Journal of Medicine — Chronic Discoid Lupus ErythematosusTreatment with Daraprim and Chloroquine Diphosphate Aralen

    Systemic lupus erythematosus has fascinated physicians for almost a century and remains the prototypic autoimmune disease. Treatment approaches emphasize using a combination of drugs to minimize chronic exposure to corticosteroids.

    Treatment of discoid lupus erythematosus with chloroquine

    PDF Successful treatment of discoid lupus erythematosus., Successful Treatment of Discoid Lupus Erythematosus with.

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  5. Hydroxychloroquine and chloroquine with or without quinacrine are currently utilized in the treatment of discoid lupus erythematosus. Hydroxychloroquine is preferred over chloroquine due to the lower risk of side effects, specifically retinal toxicity. Thalidomide, a potent teratogen, has been used in the treatment of discoid lupus erythematosus.

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    Two cases of subacute disseminated lupus erythematosus were also treated with chloroquine sulphate with no satis-factory clinical response. Summary and Conclusions Eighteen cases of chronic discoid lupus erythematosus were treated with chloroquine sulphate by mouth. The results are tabulated and discussed. Aug 21, 2018 Hydroxychloroquine is the first-line systemic agent for discoid lupus erythematosus DLE, whereas chloroquine is considered second-line antimalarial therapy in the United States. In addition, lenalidomide may be useful in some patients. 30 Hydroxychloroquine is the first-line systemic agent for discoid lupus erythematosus DLE, whereas chloroquine is considered.

     
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    Chloroquine is an anti-malaria medicine that works by interfering with the growth of parasites in the red blood cells of the human body. Remdesivir and chloroquine effectively. - Cell Research Chloroquine in Cancer Therapy A Double-Edged Sword of. Chloroquine and hydroxychloroquine for cancer therapy
     
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    Chloroquine Side Effects Common, Severe, Long Term. Change in hair color; hair loss; increased sensitivity of the skin to sunlight; redness or other discoloration of the skin; severe sunburn; stomach cramps; trouble sleeping; weight loss; For Healthcare Professionals. Applies to chloroquine compounding powder, injectable solution, oral tablet. Ocular. Maculopathy and macular degeneration may be irreversible.

    Hydroxychloroquine DermNet NZ