Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking hydroxychloroquine: Incidence not known Some side effects of hydroxychloroquine may occur that usually do not need medical attention. Chloroquine rheumatoid arthritis Will plaquenil stop hair loss Chloroquine treatment of berghei i.p Chloroquine-primaquine-phosphate. One of the most significant side effects of the drug is its possibility of causing eye problems resulting in blurred or decreased vision. The most common issue is damage to the retina. It can impair your color vision or damage the retinal cells particularly in the area right around the central vision. Plaquenil Side-Effects. What is Plaquenil and how does it affect your eyes? Plaquenil Hydroxychloroquine is a medication that is used often to treat conditions such as Rheumatoid Arthritis, Lupus Sarcoidosis, and additional autoimmune disorders. Plaquenil has been known to cause retinopathy or damage to the retina. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Side effects of plaquenil on eyes Hydroxychloroquine-Induced Retinal Toxicity - American., Plaquenil Hydroxychloroquine cautionsPlaquenil ppd test If you believe that your health is not improved but even worse then before, you should change therapy. At first, I had great relief from this drug, but later side effects developed mostly headaches bothered me. My eyes are painful, sometimes swollen and irritated, so I need to close them and take a break for some time. Eyes pain while on Plaquenil Other Drugs discussions.. Rx Side Effects New Plaquenil Guidelines and More.. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Aug 29, 2014 This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. The side effect that is of greatest concern is retinal toxicity. Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. The most important affect of Plaquenil on your eye is to damage the retina at the back of your eye. Fortunately, this is very uncommon and generally only occurs in patients on high doses or patients with bad kidney function.