It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Chloroquine-resistant plasmodium falciparum Plaquenil sde effect jittery Warfarin interaction with hydroxychloroquin Solubility of chloroquine in water The effect of hydroxychloroquine on haemostasis, complement, inflammation and angiogenesis in patients with antiphospholipid antibodies Karen Schreiber Thrombosis & Haemophilia Centre, Guy's and St Thomas' NHS Foundation Trust, London, UK RARE side effects. If experienced, these tend to have a Severe expression. Abnormal Liver Function Tests. Acute Liver Failure. Acute Pustular Eruptions On Skin. Bronchospasm. Decreased Blood Platelets. Decreased White Blood Cells. Aug 14, 2017 Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine effect on platelets Hydroxychloroquine MedlinePlus Drug Information, Common and Rare Side Effects for Plaquenil Oral Hydroxychloroquine retinopathy and night visionPlaquenil and cold medicineWhat is plaquenil 200mgPlaquenil success stories Hydroxychloroquine typically is very well tolerated. Serious side effects are rare. The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Rarely, hydroxychloroquine can lead to anemia in PATIENT FACT SHEET Hydroxychloroquine Plaquenil. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Hydroxychloroquine as an anti-thrombotic in antiphospholipid.. Effects of Hydroxychloroquine in Patients With Cutaneous Lupus Erythematosus A Multicenter, Double‐Blind, Randomized, Parallel‐Group Trial N. Yokogawa Tokyo Metropolitan Tama Medical Center, Tokyo, Japan Feb 19, 2020 Hydroxychloroquine, like chloroquine, is a weak base and may exert its effect by concentrating in the acid vesicles of the parasite and by inhibiting polymerization of heme. It can also inhibit certain enzymes by its interaction with DNA. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects.