One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil does it cause bone loss Plaquenil grapefruit Multimodal imaging set showing drusen-like deposits DLDs affecting both eyes in a patient diagnosed with systemic lupus erythematosus SLE. In the color fundus photographs Top/Third rows, left, DLDs are seen as multiple yellowish lesions of different sizes spread across the posterior pole, but mainly located in the temporal region. Figure 1 Color fundus photography and Humphrey visual field HVF testing, both eyes A Right eye has peripapillary atrophy and small macular drusen. B Left eye had peripapillary atrophy, superior optic nerve pallor with trace edema, and small macular drusen. Higher magnification of the right optic nerve C and the left optic nerve D are. Plaquenil Toxicity Plaquenil hydroxychloroquine is a medicine commonly used to treat patients with systemic lupus erythematosus and rheumatoid arthritis. After prolonged use, it can sometimes damage the macula and cause central vision loss. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Drusen plaquenil Prescription Medications That Can Affect Age-Related., Successive Presentation of Arteritic and Non-arteritic. Hydroxychloroquine diabetesBuy hydroxychloroquine sulfate onlineShow me a picture of hydroxychloroquine Note the two different phenotypes present in this image There are both Drusen – which are located in the sub-RPE space, and Subretinal Drusenoid Deposits SDD – aka pseudodrusen – located in theyou guessed itsubretinal space. You can see the one below riding on the back of a drusen with the ELM draped over Continue reading Subretinal Drusenoid Deposits vs. Drusen → Subretinal Drusenoid Deposits vs. Drusen - OCTMD. Plaquenil Louisville KY Eye Exam Elizabethtown KY Bennett.. Optical Coherence Tomography in Age-related Macular.. Drusen. The appearance of drusen — yellow deposits — in the retina indicates the development of early-stage dry macular degeneration left. As the condition progresses to the advanced stage right, the drusen get larger, bleeding occurs and the light-sensitive cells that make up the macula become scarred. Oct 21, 2010 Introduction. The use of hydroxychloroquine HCQ, an antimalarial drug utilized for a range of rheumatologic and dermatologic diseases, is associated with a low incidence of retinopathy 0.5% when used at recommended doses 6.5 mg/kg per day.1 It has largely replaced chloroquine because of decreased ocular toxicity at high dosages,2 but can still lead to potentially irreversible visual loss. Dr. Marmor’s research team also recommended that screening should be performed within the first year of initiating therapy, and then annually after five years of Plaquenil use. The risk for retinal toxicity begins once the patient has used Plaquenil for five to seven years and/or has taken a cumulative dose of more than 1,000g.