Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Does plaquenil affect immune system Chloroquine prescribing information Hydroxychloroquine dyschromia Small amounts of hydroxychloroquine can be found in breastmilk, but international experts indicate this medication is acceptable while breastfeeding. MECHANISM OF ACTION. Plaquenil increases the pH of lysosomes and impairs complement-dependent antigen-antibody reactions. It also inhibits the chemotaxis of eosinophils and locomotion of neutrophils. How to use Plaquenil. Hydroxychloroquine is usually taken with food or milk to prevent stomach upset. The dosage and length of treatment are based on your medical condition and response to therapy. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. Plaquenil hydrochloroquine Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Plaquenil Oral Uses, Side Effects, Interactions, Pictures. Plaquenil liverChloroquine prophylaxisChloroquine and proguanil during pregnancyPancreatitis and plaquenil HYDROXYCHLOROQUINE is used to treat rheumatoid arthritis and systemic lupus is also used to treat malaria. The lowest GoodRx price for the most common version of generic Plaquenil is around $20.41, 88% off the average retail price of $177.73. What is Plaquenil? - GoodRx. Hydroxychloroquine Plaquenil. Plaquenil Hydroxychloroquine Sulfate - Sanofi. Plaquenil hydroxychloroquine has been shown to improve physical function in up to 80% of patients with rheumatoid arthritis. Plaquenil hydroxychloroquine is commonly used for lupus in children because of less side effects compared to other medications. Plaquenil hydroxychloroquine helps minimize joint damage. Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used.