Fluconazole for

Discussion in 'Canadian Meds' started by Kristo, 09-Sep-2019.

  1. schenkh XenForo Moderator

    Fluconazole for


    QT prolongation Torsades de pointes Alopecia Anaphylactic reactions Angioedema Cholestasis Dizziness Dyspnea Hepatic failure Hepatitis Hypertriglyceridemia Hypokalemia Increased alkaline phosphatase Increased ALT/AST Jaundice Leukopenia Pallor Seizures Stevens-Johnson syndrome Taste perversion Thrombocytopenia Toxic epidermal necrolysis Hypersensitivity to other azoles Use caution in proarrhythmic conditions and renal impairment Use extreme caution or avoid in congenital long-QT patients and patients with conditions that increase QT-prolongation risk Fluconazole inhibits CYP2C9, CYP2C19, and CYP3A4 isoenzymes; coadministration with drugs that are substrates if these isoenzymes may be contraindicated or warrant dosage modifications Capsules contain lactose and should not be given to patients with rare hereditary problems of galactose intolerance, Lapp lactase deficiency, or glucose-galactose malabsorption Powder for oral suspension contains sucrose and should not be used in patients with hereditary fructose, glucose/galactose malabsorption or sucrase-isomaltase deficiency Syrup contains glycerol; may cause headache, stomach upset, and diarrhea Hepatotoxicity reported with use; use with caution in patients with hepatic impairment Rare exfoliative skin disorders reported; monitor closely if rash develops and discontinue if it progresses When driving vehicles or operating machines, it should be taken into account that dizziness or seizures may occasionally occur Candida krusei is inherently resistant Convenience and efficacy of single dose oral tablet of fluconazole regimen for the treatment of vaginal yeast infections should be weighed against acceptability of higher incidence of drug related adverse events with fluconazole (26%) versus intravaginal agents (16%) If drug is used during pregnancy or if patient becomes pregnant while taking the drug, patient should be informed of potential hazard to fetus; effective contraceptive measures should be considered in women of child-bearing potential who are being treated with 400 to 800 mg/day and should continue throughout the treatment period and for approximately 1 week (5 to 6 half-lives) after the final dose Highly selective inhibitor of fungal cytochrome P-450-dependent enzyme lanosterol 14-alpha-demethylase Subsequent loss of normal sterols correlates with accumulation of 14 alpha-methyl sterols in fungi and may be responsible for the fungistatic activity of fluconazole Additive: TMP-SMX Y-site: Amphotericin B, amphotericin B cholesteryl sulfate, ampicillin, calcium gluconate, cefotaxime, ceftazidime(? ), ceftriaxone, cefuroxime, chloramphenicol, clindamycin, co-trimoxazole, diazepam, digoxin, erythromycin lactobionate, furosemide, haloperidol, hydroxyzine, imipenem/cilastatin, pentamidine, piperacillin, ticarcillin, TMP-SMX Solution: D5W, LR Additive: Acyclovir, amikacin, amphotericin B, cefazolin, ceftazidime, ciprofloxacin, clindamycin, gentamicin, heparin, meropenem, metronidazole, morphine, piperacillin, potassium chloride, ranitidine with ondansetron, theophylline Y-site: Acyclovir, aldesleukin, allopurinol, amifostine, amikacin, aminophylline, amiodarone, ampicillin-sulbactam, aztreonam, benztropine, bivalirudin, cefazolin, cefepime, cefotetan, cefoxitin, cefpirome, chlorpromazine, cimetidine, cisatracurium, dexamethasone sodium phosphate, dexmedetomidine, diltiazem, diphenhydramine, dobutamine, docetaxel, dopamine, doxorubicin liposomal, droperidol, etoposide PO4, famotidine, fenoldopam, filgrastim, fludarabine, foscarnet, ganciclovir, gatifloxacin, gemcitabine, gentamicin, granisetron, heparin, hetastarch, hydrocortisone, immune globulin, leucovorin, linezolid, lorazepam, melphalan, meperidine, meropenem, metoclopramide, metronidazole, midazolam, morphine, nafcillin, nitroglycerin, ondansetron, oxacillin, paclitaxel, pancuronium, penicillin G, phenytoin, piperacillin-tazobactam, prochlorperazine, promethazine, propofol, quinupristin-dalfopristin, ranitidine, remifentanil, sargramostim, tacrolimus, teniposide, theophylline, thiotepa, ticarcillin-clavulanate, tobramycin, vancomycin, vecuronium, vinorelbine, zidovudine Tablets: Store below 86° F (30° C) Dry powder: Store below 86° F (30° C); reconstituted suspension should be stored between 86° F (30° C) and 41° F (5° C), and unused portion should be discarded after 2 weeks; protect from freezing Injection (glass bottles): Store between 86° F (30° C) and 41° F (5° C); protect from freezing Injection (Viaflex Plus plastic containers): Store between 77° F (25° C) and 41° F (5° C); protect from freezing The above information is provided for general informational and educational purposes only. Individual plans may vary and formulary information changes. Contact the applicable plan provider for the most current information. This leaflet is about the use of fluconazole for the treatment and prevention of certain yeast and fungal infections. This leaflet has been written specifically for parents and carers about the use of this medicine in children. Our information sometimes differs from that provided by the manufacturer, because their information is usually aimed at adult patients. Keep it somewhere safe so that you can read it again. Fluconazole Brand names: Diflucan® Your child has an infection caused by a yeast or fungus. Fluconazole causes damage to the membrane of yeast and fungal cells and stops the cells growing and multiplying. This gets rid of the infection, or stops an infection from developing. Some of the yeast or fungus may remain after the infection has gone. However, in babies this may be once every two or three days.

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    Drug information on Fluconazole for patients and consumers. Jan 31, 2006. Abstract. Candida spp. are responsible for most of the fungal infections in humans. Available since 1990, fluconazole is well established as a. Original Article from The New England Journal of Medicine — Fluconazole for the Treatment of Cutaneous Leishmaniasis Caused by Leishmania major.

    It comes as a tablet or suspension you take by mouth. Fluconazole oral tablet is available as both a generic drug, and as the brand-name drug Diflucan. Generic drugs usually cost less than the brand-name version. In some cases, they may not be available in all strengths or forms as the brand-name drug. Fluconazole is used to prevent and treat candidiasis. This condition is caused by infection with one of the many types of the fungus Examples of candidiasis include vaginal yeast infection, as well as oral yeast infection (thrush). Candidiasis can also cause infections on other parts of your body, including your throat, esophagus, lungs, and blood. Fluconazole is used to treat fungal infections, including yeast infections of the vagina, mouth, throat, esophagus (tube leading from the mouth to the stomach), abdomen (area between the chest and waist), lungs, blood, and other organs. Fluconazole is also used to treat meningitis (infection of the membranes covering the brain and spine) caused by fungus. Fluconazole is also used to prevent yeast infections in patients who are likely to become infected because they are being treated with chemotherapy or radiation therapy before a bone marrow transplant (replacement of unhealthy spongy tissue inside the bones with healthy tissue). Fluconazole is in a class of antifungals called triazoles. It works by slowing the growth of fungi that cause infection. Fluconazole comes as a tablet and a suspension (liquid) to take by mouth. It is usually taken once a day, with or without food.

    Fluconazole for

    Fluconazole Side Effects, Dosage, Uses, and More - Healthline, Fluconazole for the management of invasive candidiasis where do.

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  4. Urol Int. 1997;594252-6. Oral fluconazole for Candida urinary tract infection. Potasman I1, Castin A, Moskovitz B, Srugo I, Nativ O. Author information

    • Oral fluconazole for Candida urinary tract infection. - NCBI.
    • Fluconazole for the Treatment of Cutaneous Leishmaniasis Caused..
    • Fluconazole for the management of invasive candidiasis. - NCBI - NIH.

    Medscape - Candidia infection dosing for Diflucan fluconazole, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy. Dose and method of administration. Dose. The daily dose of fluconazole should be based on the nature and severity of the fungal infection. Most cases of. Find patient medical information for Fluconazole Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings.

     
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