After the fevers I get severe chilblains on my fingers, ears and toes. This I have always attributed to the Raynauds I was diagnosed with as a child. Plaquenil for malaria mechanism Plaquenil and cellcept 10-2 visual field test plaquenil need a lens Plaquenil comes in 200 milligram mg tablets that are taken by mouth. To prevent malaria in adults, two tablets are typically taken once a week, on the same day each week. Aug 26, 2016 I went to see a new rheum and he took me off the Plaquenil to see what symptoms would show. I have not been formally diagnosed yet. It took 6 weeks to see the results. I went into a bad flare. Went back to rheum and he decided to put me on Methotrexate. I have only taken it once, so I am not sure what the results will be. I am just now coming off 300 mg Plaquenil after 9 years as it is likely causing bone marrow failure -- another very rare reaction. I wonder, now that it is more prescribed and has been for over a decade, if more of us will see previously unknown ill effects. So the reason for the post is to know if anyone here has had similar issues with unexplained fevers that cause chilblains? They typically form in the evenings and hurt like hell. It very mild case that is actually more sensitive to heat then cold. When i went off plaquenil i got fevers Going off plaquenil - perhaps starting Imuran, Stopping Plaquenil - General Discussion - Life With Lupus Plaquenil cause anemiaPlaquenil and ldnMalaria tablets chloroquine and proguanil side effectsHydroxychloroquine pregnacy Oct 22, 2019 In 2002 I got a new doctor that diagnosed me with SLE and started me on plaquenil. I don't remember exactly how long it took but after some months the fever went down. I have always had fatigue after my first flare and joints and muscle pain every day along with many respiratory infections and skin rashes. But the fever has stayed away. Unexplained fever - @KristinOsp - Lupus - 20191022 - Inspire. Plaquenil, a warning. lupus. Plaquenil Hydroxychloroquine for use in Autoimmune disease.. Plaquenil is really a drug developed for Malaria, but when they gave it to the people with malaria who also had osteoarthitis in their fingers and toes, it stopped it. I also have Rheumatoid Arthritis, which I have had since I was five years old. I also have Osteoporosis, and I am going to get an infusion of Reclast this week. Plaquenil is a slow-acting drug, meaning that it can take up to 6 months to experience the full benefits of this medication, but it is possible for symptoms to improve in as few as 1 or 2 months. Plaquenil and other antimalarials are the key to controlling lupus long-term, and some lupus patients may be on Plaquenil for the rest of their lives. Re should I take Plaquenil now or wait? Hi. I'm obviously only a patient, but it's my understanding that you can have cutaneous lupus---discoid, hypertrophic, etc.---without having positive serology.