So far I have no more energy than when I first started and has developed neuropathy which I have just found out from Web MD that this neuropathy is one of the side effects of this med! Saying that by stopping this it would take another 6 months to build up the benefit. There are other meds that can help with what you are experiencing, and if your doctor didn't address that then I would seek out a second opinion... Please don't stop your plaquenil until you are sure it is the right thing to do and in your best interest. Can plaquenil cause numbness in tailbone area and legs What is chloroquine resistance I'm on Plaquenil, and after the first week's GI upset, I have had no problems with it. Did you take yourself off Plaquenil, or did your doctor tell you to go off it? And as far as the vision issue goes, toxicity causing vision loss is very rare if you are on the right dose for your height and if you get regular eye exams. Feb 19, 2020 SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. HSS study identifies that a new treatment option called tocilizumab may help treat patients living with polymyalgia rheumatica, which causes muscle pain and stiffness, New Treatment Option May Be on the Horizon for Polymyalgia Rheumatica Plaquenil is a 6-weeker as far as the benefits are concerned, but it would be more dangerous to stop if you spend a lot of time outside and if this were the summer. Or maybe another doctor if you're not comfortable w/your current one. Does going off plaquenil cause fever after surgery Hold the immunomodulators for surgery? Maybe yes, maybe no., Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Plaquenil skin rashIs plaquenil discontinuedPlaquenil ask doctorLong term plaquenil therapy So that's the update. The lesson here is - for those who need to go off plaquenil, be careful about just going off it cold turkey. Obviously some of CAN do that, but if you don't know if you're one of them - better to be on the safe side and wean slowly. Take it from me! I am feeling much better after bumping my dose back up over the last few. Let me tell you what weaning down from Plaquenil is like.. New Treatment Option May Be on the Horizon for Polymyalgia.. The Risk of Retinal Toxicity with Plaquenil. I stopped taking the plaquenil the beginning of December. It doesn't agree with my stomach I take it with meals too. And since I hadn't had a miraculous recovery the 6 months I'd been on it, I didn't think there was any harm in stopping it. BUT after being off it for a month and a half my body feels like it's falling apart. The Monday after Thanksgiving I went to my GP and she sent me to my Dermatologist immediately. I told him i felt like it was from the Plaquenil he agreed. I came off of it that day and my symptoms have gotten worse. I have had biopsies of my skin but still waiting for the results. I was told this is going to take over a month to get out of my. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used. Quinacrine.