Chloroquine as antiinflammatory

Discussion in 'Canada Pharmacy Online' started by shmuk, 10-Mar-2020.

  1. Chloroquine as antiinflammatory


    Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

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    Chloroquine is a 9-aminoquinoline known since 1934. Apart from its well-known antimalarial effects, the drug has interesting biochemical properties that might be applied against some viral infections. Chloroquine exerts direct antiviral effects, inhibiting pH-dependent steps of the replication of several viruses including members of the flaviviruses, retroviruses, and coronaviruses. Its best. Chloroquine is an aminoquinoline used for the prevention and therapy of malaria. It is also effective in extraintestinal amebiasis and as an antiinflammatory agent for therapy of rheumatoid arthritis and lupus erythematosus. Chloroquine is not associated with serum enzyme elevations and is an extremely rare cause of clinically apparent acute liver injury. The ADF no longer uses chloroquine as an anti-malarial medication because the malaria parasites in countries that the ADF deploys to have become resistance to it, meaning it is no longer effective. Chloroquine is generally well tolerated but not suitable for people with epilepsy or existing eye disease.

    Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria.

    Chloroquine as antiinflammatory

    Asthma, Steroids, and Other Anti-Inflammatory Drugs, Chloroquine - LiverTox - NCBI Bookshelf

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  6. Chloroquine is a 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite.

    • Chloroquine C18H26ClN3 - PubChem.
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    Chloroquine A 4-aminoquinoline with antimalarial, anti-inflammatory, and potential chemosensitization and radiosensitization activities. Although the mechanism is not well understood, chloroquine is shown to inhibit the parasitic enzyme heme polymerase that converts the toxic heme into non-toxic hemazoin, thereby resulting in the accumulation of toxic heme within the parasite. For over a half-century the anti-malarial drug chloroquine CQ has been used as a therapeutic agent, alone or in combination, to treat autoimmune diseases. However, neither the underlying. The Spondylitis Association of America is the only non-profit organization in the United States dedicating its resources to the active support of ankylosing spondylitis patients to bring about awareness, education, and research to ensure a better life for all spondylitis patients.

     
  7. AxiododikeKed Well-Known Member

    I don't know if anyone can help as this isn't technically lupus related. If you've stopped taking plaquenil, did you start getting. What is the correct way to discontinue use of plaquenil? Had to stop taking Plaquenil -
     
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    The page you are trying to reach is not available on our site. The page name may have changed, you may have happened upon a broken link, or the URL may be entered incorrectly. Plaquenil, Bells Palsy and Eye Care - This Lupus Life Itchy, Red Eyes? How to Tell If It’s Allergy or Infection – Health. Tearing in one eye and Watery eyes Common Related Medical Conditions
     
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