Metoprolol classification

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    Metoprolol classification


    If you have a heart attack, your doctor may give you metoprolol tartrate (Lopressor). This drug can prevent another heart attack from occurring. However, you should be careful not to confuse it with metoprolol succinate (Toprol-XL). While the two drugs share the same first word and both treat heart-related issues, metoprolol succinate doesn’t prevent or treat a heart attack in people who’ve already had a heart attack. Learn more about the similarities and differences between these two drugs. Metoprolol tartrate and metoprolol succinate contain the same active medication: metoprolol. These salt forms, tartrate and succinate, are approved by the U. Food and Drug Administration (FDA) for different conditions. Both medications belong to a class of drugs called beta-blockers, which work by relaxing your blood vessels and slowing down your heart rate. Metoprolol is a cardioselective β1-adrenergic blocking agent used for acute myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension. It may also be used for supraventricular and tachyarrhythmias and prophylaxis for migraine headaches. Metoprolol is structurally similar to bisoprolol, acebutolol and atenolol in that it has two substituents in the para position of the benzene ring. The β1-selectivity of these agents is thought to be due in part to the large substituents in the para position. At low doses, metoprolol selectively blocks cardiac β1-adrenergic receptors with little activity against β2-adrenergic receptors of the lungs and vascular smooth muscle. Unlike propranolol and pindolol, metoprolol does not exhibit membrane-stabilizing or intrinsic sympathomimetic activity. Membrane-stabilizing effects are only observed at doses much higher than those needed for β-adrenergic blocking activity. Metoprolol possesses a single chiral centre and is administered as a racemic mixture.

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    Metoprolol C15H25NO3 CID 4171 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities. Jul 23, 2014. Metoprolol is the generic form of the brand-name drug Lopressor, prescribed to treat high blood pressure and prevent angina chest pain. Metoprolol ist ein Arzneistoff aus der Gruppe der selektiven β1- Adrenorezeptorenblocker Betablocker und wird zur Behandlung des Bluthochdrucks, der.

    Absorption: Well absorbed after oral administration. Distribution: Crosses the blood-brain barrier, crosses the placenta; small amounts enter breast milk. Metabolism and Excretion: Mostly metabolized by the liver (primarily by CYP2D6; the CYP2D6 enzyme system exhibits genetic polymorphism); ~7% of population may be poor metabolizers and may have significantly ↑ metoprolol concentrations and an ↑ risk of adverse effects. TIME/ACTION PROFILE (cardiovascular effects)When switching from immediate-release to extended-release product, the same total daily dose can be used PO: (Adults) Antihypertensive/antianginal– 25–100 mg/day as a single dose initially or 2 divided doses; may be ↑ q 7 days as needed up to 450 mg/day (immediate-release) or 400 mg/day (extended-release) (for angina, give in divided doses). MI– 25–50 mg (starting 15 min after last IV dose) q 6 hr for 48 hr, then 100 mg twice daily. Heart failure– 12.5–25 mg once daily (of extended-release), can be doubled every 2 wk up to 200 mg/day. Migraine prevention– 50–100 mg 2–4 times daily (unlabeled). IV: (Adults) MI– 5 mg q 2 min for 3 doses, followed by oral dosing. Tablets (tartrate): 25 mg, 50 mg, 100 mg Cost: Generic: All strengths $7.18/100Extended-release tablets (succinate; Toprol XL): 25 mg, 50 mg, 100 mg, 200 mg Cost: Generic: 25 mg $35.68/100, 50 mg $41.93/100, 100 mg $53.95/100, 200 mg $84.54/100Solution for injection: 1 mg/m LIn Combination with:hydrochlorothiazide (Dutoprol, Lopressor HCT). See combination drugs.metoprolol is a sample topic from the Davis's Drug Guide. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when you suddenly stop this drug. Some people who have suddenly stopped taking similar drugs have had chest pain, heart attack, and irregular heartbeat. If your doctor decides you should no longer use this drug, he or she may direct you to gradually decrease your dose over 1 to 2 weeks. When gradually stopping this medication, it is recommended that you temporarily limit physical activity to decrease strain on the heart. Get medical help right away if you develop chest pain/tightness/pressure, chest pain spreading to the jaw/neck/arm, unusual sweating, trouble breathing, or fast/irregular heartbeat. Show More Metoprolol is used with or without other medications to treat high blood pressure (hypertension). Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.

    Metoprolol classification

    Metoprolol - DrugBank, Metoprolol Lopressor - Side Effects, Dosage, Interactions - Drugs

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  5. Metoprolol answers are found in the Davis's Drug Guide powered by Unbound. Lopresor SR Canadian Tradename; Lopressor; Toprol-XL. Ther. Class.

    • Metoprolol Davis's Drug Guide.
    • Metoprolol – Wikipedia.
    • Metoprolol - Wikipedia.

    Both versions of metoprolol belong to a class of drugs called beta-blockers. A class of drugs is a group of medications that work in a similar way. These drugs are. Sep 15, 2017. Metoprolol learn about side effects, dosage, special precautions, and more on MedlinePlus. Metoprolol Lopressor antianginals, IV or doses, followed by oral dosing antihypertensives PODocuments Similar To Generic Name T Rade Name Classification Metoprolol Lopressor.

     
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