He had a history of rheumatoid arthritis, and had been treated with hydroxychloroquine for the last 8 years. Echocardiography revealed a left ventricular ejection fraction of 25%, with diffuse hypokinesis. Hydroxychloroquine lung disease Can i take benadryl with plaquenil Plaquenil and eye photosensitivity The drug plaquenil See All Issues; Circ Heart Failure. Journal Home; Current Issue; See All Issues; Circulation Research. Journal Home; Current Issue; See All Issues; Hypertension. Journal Home; Current Issue; See All Issues; Stroke. Journal Home; Current Issue; See All Issues; Journal of the American Heart Association JAHA Journal Home; Current Issue; See All. What is Plaquenil? Plaquenil hydroxychloroquine is a medication most known for its original purpose of treating or preventing malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. The differential diagnosis for new onset non-ischemic cardiomyopathy in this patient included inflammatory cardiomyopathy, viral myocarditis, sarcoidosis, amyloidosis, hemochromatosis, Fabry's disease and HCQ toxicity. Coronary angiography demonstrated non-obstructive coronary disease. Treatment was initiated with guideline directed medical therapy, and patient clinically improved. Plaquenil and heart issues Increasing plaquenil, having problems, Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Does hydroxychloroquine require a prescriptionChloroquine rheumatoid arthritis mechanism of actionHow does plaquenil help ra Sep 13, 2017 We present a case of twin sisters who both suffered from systemic lupus erythematosus SLE and HCQ-induced cardiomyopathy presenting with decompensated heart failure HF, suggesting that genetic predisposition might be a factor in HCQ-induced cardiomyopathy. Hydroxychloroquine-induced cardiomyopathy and heart failure.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs. Plaquenil hydroxychloroquine is in a class of drugs called disease-modifying anti-rheumatic drugs, which are used to decrease inflammation, pain and joint damage. While today it is used to treat autoimmune conditions, such as rheumatoid arthritis and lupus, it was originally used as an anti-malaria drug. Plaquenil can cause serious liver or heart problems, especially if you use certain medicines at the same time, including other medicines to treat malaria; an antibiotic or antifungal medicine; antiviral medicine to treat hepatitis or HIV/AIDS; antidepressants or antipsychotic medicines; birth. We present a case of twin sisters who both suffered from systemic lupus erythematosus SLE and HCQ-induced cardiomyopathy presenting with decompensated heart failure HF, suggesting that genetic predisposition might be a factor in HCQ-induced cardiomyopathy.