At first it seemed like it helped now I feel the same as before I started taking the medicine other than the fact that none of my clothes fit and there is a lot more of me to carry around. Anyone know if I quit taking it if the weight will fall back off I started Hydroxychloroquine 2 weeks ago. One week in and I thought this may just work, except for the ‘extra itchiness’ I seemed to get every night. Plaquenil and mood Chloroquine use in sle There seem to be mainly negative experiences here so by way of balance I can say I had only one very mild side effect - mild nausea for around an hour a day but nothing that stopped me going to work, working out, etc and it stopped after a couple of months. That was two years ago. I started plaquenil about 8 months ago. Before that I was bedridden. I also have fibromyalgia and cfs but the plaquenil did save my life. It did not make me normal of course but I can do a lot more now than before. I don’t have any side effects and even if I had a few it would still be worth taking. You will need it! Trust in the plaquenil.effects everyone differently of course, but in my experience it has been most helpful in my UCTD treatment. I too was on pred for a looong time, thankfully I am off of it now and somewhat stable, so give the plaquenil a chance and keep smiling hugs I was prescribed this drug to ease my ra disease, I was taking 400mg per day which was to last for 3 months then reduced to 200mg. Right before I hit the two week mark, I woke up with my heart racing and continued feeling my heart flutter all day and I just felt week and tired. After msging Rheum, decided to stop taking meds to see how I feel and continue with the AIP to handle symptoms and try to work at ‘healing from inside out! Time will tell and I’m eager to see how much the AIP is helping once odd meds. Experiences with plaquenil Your personal experience with plaquenil DailyStrength, Experiences with plaquenil? Sjogren's Syndrome Forums. Chloroquine hydrochloride sigmaPlaquenil retinopathy risk factorsWhat chloroquineTake plaquenil with vitaminsChloroquine torsades What's your experience with plaquenil? → Shop Live Hope Lupus Merch I appreciate your support → Check out my Amazon Store. PLAQUENIL hydroxychloroquine Benefits & Side Effects.. UCTD and Plaquenil DailyStrength. Does anyone have experience with Plaquenil and br.. Plaquenil has been a life-saving drug for me, quite literally. I was a mess in 2004-2005 and then a dr put me on Plaquenil, and in 3 weeks most of my symptoms had disappeared. Experiences with Plaquenil Hydroxychloroquine? I've recently been referred to a rheumatologist for joint pain arthralgia with a low titre positive ANA. At our first visit she ran tons of blood work/antibody tests only Thyroid Peroxidase Antibodies came back positive and also put me on low dose prednisone for a couple of weeks. I have been taking Plaquenil for just 5 weeks. I started it reluctantly after months of trying diet and acupuncture. I am sticking to the low-lectin diet and monthly acupuncture but in the last 10 days I have noticed a very distinct decrease in my joint pain and swelling and my fatigue has definitely lifted a little.